RTFA: http://www.economist.com/displaystory.cfm?story_id…

TASTELESS, colourless, odourless and painful, pure capsaicin is a curious substance. It does no lasting damage, but the body s natural response to even a modest dose such as that found in a chili pepper is self-defence: sweat pours, the pulse quickens, the tongue flinches, tears may roll. But then something else kicks in: pain relief. The bloodstream floods with endorphins-the closest thing to morphine that the body produces. The result is a high. And the more capsaicin you ingest, the bigger and better it gets.

Which is why the diet in the rich world is heating up. Hot chilies, once the preserve of aficionados with exotic tastes for cuisine from places such as India, Thailand or Mexico, are now a staple ingredient in everything from ready meals to cocktails.

Wait for it …

Among other things, that may give a scientific explanation for the habit, not formally researched, of snorting the “pink fix” (a mixture of cocaine and chili powder).

Crikey!

This is a fabulously informative and interesting article; all “heat geeks” must RTFA. In addition to describing the neural pathways and scientific studies regarding our perception of spicy foods, the article is chock full of hilarious tidbits and has good external links.

RTFA: http://www.nsf.gov/discoveries/disc_summ.jsp?cntn_…

Earlier this year, consumers around the world noticed higher food prices as the cost of most grains escalated. In many parts of the developing world, rice, a crucial staple for billions of people, became too expensive or not available at all, triggering large-scale hunger and food riots that destabilized entire countries and regions.

In May of this year, a group of computational biologists at the University of Washington began to tap the collective power of more than 1 million desk top computers to better understand the protein structures of rice plants …, the Nutritious Rice for the World project … Led by Ram Samudrala, an associate professor and computational biologist at the University of Washington, the project taps the World Community Grid, a distributed computing system created by IBM that links up computers all over the planet. The grid combines the spare power of computers not in use to handle large-scale computational problems such as analyzing rice genomics.

The project is one of five initiatives being tackled by the World Community Grid right now and, according to Samudrala, it is taking up about a third of the grid’s current capacity. By using the collective power of the grid, Samudrala and his collaborators estimate the project will be completed in two years, considerably faster than the 200 years they estimate it would take a conventional computer system to complete the same job.

Ultimately, the combined power of these computers should allow the researchers to map out the 30,000 to 60,000 rice protein structures and better understand their related functions. Armed with this information, plant biologists should be able to begin to provide the world’s farmers with rice varieties that can grow with less water, resist insects and diseases and provide a more nutritious meal.

… Given the large number of people who eat rice as their primary source of grain, this research could go a long way in tackling some of the food security challenges currently facing the human race.

This project demonstrates the power for great good that can be achieved through pure nerdiness. If you’re a bio-geek, you will probably enjoy checking out Prof. Samudrala’s website. The site is chalk chock full of goodies, including software downloads (and a web API!) to model genomes, proteins, et al. (: http://software.compbio.washington.edu/ Using their online “Bioverse” java app, I generated this DNA sequence of E. Coli and its closest evolutionary relatives … oh E. Coli: So good for the lower intestines; so bad for the stomach!